TB-500
Regenerative·4.7(3)

TB-500

Thymosin Beta-4 fragment for tissue repair research.

$70CAD · Excl. tax≈ $7.00 / mgOut of stock
Size · 1 optionsSKU PB-TB500-10
  • HPLC
    ≥99.1%
  • COA
    Signed
  • Shipping
    Vancouver
  • Origin
    🇨🇦 Vancouver

Optional Temperature Protection $9.99 CAD · 14-day analytical guarantee

Purity
99.1%
Presentation
10mg, lyophilised
Molecular formula
C₂₁₂H₃₅₀N₅₆O₇₈S
Molecular mass
4963.44 g/mol
Storage
−20°C, protected from light
Verification
HPLC · MS · Endotoxin
Batch verification
Verify by QR

What is TB-500?

TB-500 is a synthetic peptide corresponding to an active fragment of Thymosin Beta-4, a naturally occurring protein. It appears in research literature examining actin regulation and tissue-repair processes.

Peptibolics supplies TB-500 strictly as a research material for laboratory investigation.

01

Research Overview

The following summarizes areas that published scientific literature has explored. These statements describe research findings in experimental models and are provided for educational purposes only.

02

Actin regulation research

Studies have investigated TB-500's relationship to actin, a cytoskeletal protein central to cell structure and movement.

03

Cell migration and repair research

Animal-model research has explored TB-500 in the context of cell migration and tissue-repair signaling.

04

Angiogenesis research

Laboratory research has examined associations with new blood-vessel formation in experimental models.

05

Available vial sizes

10mg

06

Purity

≥99% (HPLC verified)

07

Quality & Testing

Every lot of Peptibolics TB-500 is verified by third-party laboratory analysis for identity and purity, with a certificate of analysis (COA) available for the corresponding lot.

Mechanism of action

How TB-500 interacts with cellular systems.

  • 01Sequesters G-actin, regulating actin polymerisation dynamics in migrating cells.
  • 02Upregulates VEGF and promotes endothelial cell migration in vitro.
  • 03Modulates inflammatory cytokine expression in cultured macrophages.
  • 04Enhances progenitor cell recruitment in wound-model assays.
Research applications

Where this compound appears in the literature.

  • Dermal fibroblast migration and scratch assays
  • Cardiac and skeletal muscle repair models
  • Corneal wound healing studies
  • Actin cytoskeleton dynamics research
Specifications

Analytical release specification.

Every batch is released against this specification. Batch-specific values are printed on the accompanying Certificate of Analysis.

Compound
TB-500
CAS number
77591-33-4
Sequence
Ac-LKKTETQ
Molecular formula
C₂₁₂H₃₅₀N₅₆O₇₈S
Molecular mass
4963.44 g/mol
Purity (HPLC)
≥99.1%
Mass confirmation
ESI-MS · matches theoretical
Endotoxin
< 0.5 EU/mg
Appearance
White lyophilised powder
Solubility
Water, PBS
Presentation
10mg, lyophilised · acetate salt
Storage
−20°C, protected from light
Shelf life
24 months from date of manufacture
Research use
For in vitro laboratory research only
Handling & reconstitution

Bench-ready protocol.

Reconstitution

Reconstitute with 2 mL of bacteriostatic water for a 2.5 mg/mL solution. Add solvent along the vial wall; do not shake. Allow full dissolution before use.

Handling

Use aseptic technique. Aliquot into single-use volumes to avoid freeze-thaw degradation. Discard if solution appears cloudy.

Storage

Lyophilised: −20°C. Reconstituted: 2–8°C up to 14 days, or aliquot at −20°C.

HPLC
≥99.1% purity
ESI-MS
Identity confirmed
LAL
< 0.5 EU/mg
Shipping
Vancouver → Canada-wide
Verified researcher reviews

From the labs using TB-500.

4.7
3 verified reviews

Reviews are submitted by verified researchers and institutions after batch delivery. Identity abbreviated for privacy.

  • Verified

    Reliable identity and mass spec.

    MS confirms sequence, HPLC matches the COA. Delivery from Vancouver to Toronto in 48h, packaging intact.

    A.D.Research associate — cardiac repair lab
  • Verified

    Clean scratch-assay results.

    Consistent migration data across three separate batches. Documentation is best-in-class for a Canadian supplier.

    J.P.Senior scientist — dermatology R&D
  • Verified

    Excellent, but pricing on 10mg would help.

    Quality is not in question. A larger presentation would streamline our stock management. Otherwise flawless.

    R.C.Lab manager — corneal biology
Frequently asked

Questions researchers ask us about TB-500.

Can't find your answer? Contact our lab team.

7 answered

TB-500 is supplied in Canada as a research chemical for laboratory use only. It is not approved by Health Canada for human or veterinary use and is not sold for consumption.

It is investigated in relation to actin regulation, cell migration, and tissue-repair processes in animal models.

Each lot is verified for identity and purity by third-party HPLC analysis, with a COA available.

Every batch of TB-500 is HPLC-verified to ≥99% purity, mass-confirmed by ESI-MS, and endotoxin-tested to <0.5 EU/mg. A batch-specific Certificate of Analysis is available on this page and inside every shipment.

Orders placed before 14:00 PT ship same-day from Vancouver via tracked courier. Standard transit is 1–3 business days nationwide. Optional Temperature Protection ($9.99 CAD) adds insulated packaging with phase-change coolant to maintain 2–8°C for heat-sensitive orders.

Yes. A signed COA is downloadable directly from this product page and includes HPLC chromatogram, mass spectrum, sequence confirmation, appearance, water content and endotoxin result — traceable to the batch number printed on your vial.

Peptibolics compounds are supplied strictly for in vitro laboratory research. By ordering you confirm you are a qualified researcher or institution and will not administer product to humans or animals. All sales are final.

Research use only. TB-500 is supplied strictly for in vitro laboratory research. Not for human or veterinary use. By purchasing you confirm you are a qualified researcher acting within applicable law.

Read our quality standard →
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TB-500
$70 · 10mg