MOTS-C

MOTS-C

Mitochondrial-derived signalling peptide.

$55CAD · Excl. tax≈ $5.50 / mgOut of stock
Size · 1 optionsSKU PB-MOTSC-10
  • HPLC
    ≥99.2%
  • COA
    Signed
  • Shipping
    Vancouver
  • Origin
    🇨🇦 Vancouver

Optional Temperature Protection $9.99 CAD · 14-day analytical guarantee

Purity
99.2%
Presentation
10mg, lyophilised
Molecular formula
C₁₀₂H₁₅₃N₂₉O₂₃S₂
Molecular mass
2174.60 g/mol
Storage
−20°C, protected from light
Verification
HPLC · MS · Endotoxin
Batch verification
Verify by QR

What is MOTS-C?

MOTS-c is a mitochondrial-derived peptide studied in metabolic and longevity research literature for its associations with cellular energy regulation.

Peptibolics supplies MOTS-c strictly as a research material for laboratory investigation.

01

Research Overview

The following summarizes areas that published scientific literature has explored. These statements describe research findings in experimental models and are provided for educational purposes only.

02

Metabolic regulation research

Research has investigated MOTS-c in relation to metabolic signaling and glucose utilization in animal and cellular models.

03

Mitochondrial function research

Studies have explored the peptide's association with mitochondrial activity, a topic of interest in aging and metabolism science.

04

Available vial sizes

10mg

05

Purity

≥99% (HPLC verified)

06

Quality & Testing

Every lot of Peptibolics MOTS-C is verified by third-party laboratory analysis for identity and purity, with a certificate of analysis (COA) available for the corresponding lot.

Mechanism of action

How MOTS-C interacts with cellular systems.

  • 01Modulates AMPK signalling in muscle and adipose cell models.
  • 02Influences folate-methionine cycle and one-carbon metabolism.
  • 03Regulates insulin sensitivity markers in animal studies.
  • 04Retrograde mitochondrial-to-nucleus signalling under metabolic stress.
Research applications

Where this compound appears in the literature.

  • AMPK pathway research
  • Mitochondrial biology and signalling
  • Metabolic and insulin-sensitivity models
  • Ageing and stress-response research
Specifications

Analytical release specification.

Every batch is released against this specification. Batch-specific values are printed on the accompanying Certificate of Analysis.

Compound
MOTS-C
CAS number
1627580-64-6
Sequence
MRWQEMGYIFYPRKLR
Molecular formula
C₁₀₂H₁₅₃N₂₉O₂₃S₂
Molecular mass
2174.60 g/mol
Purity (HPLC)
≥99.2%
Mass confirmation
ESI-MS · matches theoretical
Endotoxin
< 0.5 EU/mg
Appearance
White lyophilised powder
Solubility
Water, PBS
Presentation
10mg, lyophilised · acetate salt
Storage
−20°C, protected from light
Shelf life
24 months from date of manufacture
Research use
For in vitro laboratory research only
Handling & reconstitution

Bench-ready protocol.

Reconstitution

Reconstitute with bacteriostatic water for a 1 mg/mL stock.

Handling

Aseptic aliquoting recommended.

Storage

Lyophilised: −20°C. Reconstituted: 2–8°C up to 14 days.

HPLC
≥99.2% purity
ESI-MS
Identity confirmed
LAL
< 0.5 EU/mg
Shipping
Vancouver → Canada-wide
Verified researcher reviews

From the labs using MOTS-C.

4.7
3 verified reviews

Reviews are submitted by verified researchers and institutions after batch delivery. Identity abbreviated for privacy.

  • Verified

    Clean AMPK activation.

    Consistent phospho-AMPK response in myoblast assays. Peptibolics COA is signed and traceable.

    R.E.Mitochondrial biology researcher
  • Verified

    Good quality, niche compound.

    Nice to have a Canadian supplier for this. Documentation is thorough.

    W.C.PhD candidate — ageing research
  • Verified

    Excellent lot-to-lot consistency.

    Second batch is analytically indistinguishable from the first. That's the standard we need.

    Z.A.Research technician
Frequently asked

Questions researchers ask us about MOTS-C.

Can't find your answer? Contact our lab team.

7 answered

MOTS-C is supplied in Canada as a research chemical for laboratory use only. It is not approved by Health Canada for human or veterinary use and is not sold for consumption.

It is investigated in metabolic and mitochondrial-function research within the longevity literature.

Each lot is verified for identity and purity by third-party HPLC analysis, with a COA available.

Every batch of MOTS-c is HPLC-verified to ≥99% purity, mass-confirmed by ESI-MS, and endotoxin-tested to <0.5 EU/mg. A batch-specific Certificate of Analysis is available on this page and inside every shipment.

Orders placed before 14:00 PT ship same-day from Vancouver via tracked courier. Standard transit is 1–3 business days nationwide. Optional Temperature Protection ($9.99 CAD) adds insulated packaging with phase-change coolant to maintain 2–8°C for heat-sensitive orders.

Yes. A signed COA is downloadable directly from this product page and includes HPLC chromatogram, mass spectrum, sequence confirmation, appearance, water content and endotoxin result — traceable to the batch number printed on your vial.

Peptibolics compounds are supplied strictly for in vitro laboratory research. By ordering you confirm you are a qualified researcher or institution and will not administer product to humans or animals. All sales are final.

Research use only. MOTS-C is supplied strictly for in vitro laboratory research. Not for human or veterinary use. By purchasing you confirm you are a qualified researcher acting within applicable law.

Read our quality standard →
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MOTS-C
$55 · 10mg